Researcher Profile Form First National Pediatric Brain Tumor Research Meeting March 9, 2025 - Jerusalem

Researcher: Prof. Yuval Tabach
Current Role & Affiliation
Title/Position: Associate Professor; Head, The Deep Genomics Lab Institution: The Hebrew University-Hadassah Medical School
Email: yuvaltab@ekmd.huji.ac.il
Phone: 054-3973641
Website: https://www.tabach-lab.com/
Prof. Tabach leads multidisciplinary research at The Deep Genomics Lab, focusing on cancer genomics and disease gene discovery.
Research Focus
● Cancer genomics and exceptional responders
● Comparative genomics
● Disease gene discovery
● Functional genomics
Current Projects Related to Pediatric Brain Tumors
● Studies on cancer resistance mechanisms
● Genetic predisposition research
Laboratory/Research Resources
● Molecular biology and genetic analysis tools
● Functional genomics and computational platforms
Collaboration Interests
● Genomic approaches to cancer resistance
● Translational research on disease genes
Selected Achievements
● 51 publications in journals such as Nature, Cell, and Science Translational Medicine
● Development of five web tools for the research community
● Establishment of three companies
● Over €5,000,000 in competitive funding
● Identification of genetic predisposition to COVID post-vaccination myocarditis
Selected Publications
1. Canavati C, et.al. Using multi-scale genomics to associate poorly annotated genes with rare diseases. Genome Med. 2024 Jan 4;16(1):4.
2. Nair NU, et.al. Cross-species identification of cancer resistance-associated genes that may mediate human cancer risk. Sci Adv. 2022 Aug 5;8(31):eabj7176.
3. Stupp D, et. al. Co-evolution based machine-learning for predicting functional interactions between human genes.Nat Commun. 2021 Nov 9;12(1):6454.
Keywords
Cancer Genomics, Disease Genes, Functional Genomics, Comparative Genomics
Brief Bio
Dr. Tabach’s research focuses on elucidating cancer processes based on their evolutionary history. He received his BSc degree from Tel Aviv University and his PhD in Bioinformatics from the Weizmann Institute of Science. After postdoctoral training at the Massachusetts General Hospital and Harvard Medical School in Boston, he joined the Hebrew University, where he is now an Associate Professor in the Department of Developmental Biology and Cancer Research