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Researcher Profile Form First National Pediatric Brain Tumor Research Meeting March 9, 2025 - Jerusalem

Researcher: Prof. Yael Mardor

Current Role & Affiliation

Title/Position: Associate Professor, Oncology; Chief Scientist
Institution: The Advanced Technology Center, Sheba Medical Center; School of Medicine, Tel Aviv University
Email: yael.mardor@sheba.health.gov.il
Phone: 052-6667274

Prof. Mardor leads research on brain tumors, drug delivery, MRI applications, and blood-brain barrier disruption at Sheba Medical Center.

Research Focus

● Drug delivery systems

● MRI applications

● Blood-brain barrier disruption

Current Projects Related to Pediatric Brain Tumors

● Studies on BBB disruption for enhanced drug delivery

● MRI-based tissue characterization for brain tumors

● MRI-based depiction of BBB function

Laboratory/Research Resources

● MRI imaging tools

● Drug delivery platforms


Collaboration Interests

● Advanced imaging techniques

● Drug delivery strategies

What You Can Offer Potential Collaborators

● Expertise in MRI applications

● Drug delivery innovations

Recent Relevant Publications

1. Liraz-Zaltsman et al, Application of Delayed Contrast Extravasation Magnetic Resonance Imaging for Depicting Subtle Blood–Brain Barrier Disruption in a Traumatic Brain Injury Model, J of Neurotrauma, 2014.

2. Cooper et al, BBB opening by low pulsed electric fields, depicted by delayed-contrast MRI, enables efficient delivery of therapeutic Doxorubicin doses into mice brains Fluids and Barriers of the CNS, 2023.

3. Zach et al, Delayed Contrast Extravasation MRI: A New Paradigm in Neuro-Oncology, Neuro Oncol, 2014.

Keywords

MR Imaging, Brain Tumors, Drug Delivery, BBB Disruption, FUS, electroporation, TBI

Brief Bio

Prof Yael Mardor is the Chief Scientist and Head of the MR Research Group at the Advanced Technology Center of Sheba Medical Center and an Associate Professor at Tel Aviv University Medical School. After completion of her PhD in Nuclear Physics at Tel Aviv University in collaboration with Brookhaven National Lab, Prof Mardor proceeded to medical research with emphasis on brain, brain tumors, drug delivery and MRI.