Researcher Profile Form First National Pediatric Brain Tumor Research Meeting March 9, 2025 - Jerusalem
Researcher: Prof. Oded Behar
Current Role & Affiliation
Email: oded.behar@mail.huji.ac.il
Phone: 054-5696523
Prof Behar leads a laboratory looking at molecular pathways within glial tumors and brain microenvironment.Another focus of interest is brain injury and neuroinflammatory responses
Research Focus
● Pontine glioma development
● Semaphorins
● Astrocyte microglia communication
● Brain Injury
Current Projects Related to Pediatric Brain Tumors
● Evaluation of the role of multiple pathways to development of pontine glioma
Collaboration Interests
● Research relating to development and localization of high grade glial tumors in the developing brain
What You Can Offer Potential Collaborators
● Extensive experience in clinical research and development
Keywords
Neurobiology, glioma development,developmental biology, semaphorins, molecular pathways, brain injury
Recent Relevant Publications
1. Casden N, et.al. Astrocyte-to-microglia communication via Sema4B-Plexin-B2 modulates injury-induced reactivity of microglia. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2400648121.
2. Sweetat S, et.al. Improved neuron protection following cortical injury in the absence of Semaphorin4B. Front Cell Neurosci. 2022 Dec 1;16:1076281
3. Zats LP, et.al. .An affinity for brainstem microglia in pediatric high-grade gliomas of brainstem origin. Neurooncol Adv. 2022 Jul 21;4(1):vdac117.
Brief Bio.
Prof. Behar’s laboratory is involved in research re molecular pathways within high grade glial cells with interest in malignant pediatric glioma. studies evaluating multiple pathways including the role of Semaphorins, the role of interleukinss and microenvironment-tumor cells cross talk. further study involves pathways in neuroinflammation following brain injury
